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OCR: John D Brunzell MD Professor of Medicine Division of Metabolism, Endocrinology and Nutrition Department of Medicine University of Washington Seattle, Washington, USA Alan Chait MD Professor of Medicine Division of Metabolism, Endocrinology and Nutrition Department of Medicine University of Washington Seattle, Washington, USA Timothy Chard MD FRCOG Professor of Reproductive Physiology St. Bartholomew's Hospital London, UK Janet E. Dacie FRCP, DMRD, FRCR Consultant Radiologist Department of Diagnostic Radiology St. Bartholomew's Hospital London, UK